I agree with the advice on horde rules and skill challenges, as the first makes your life so much easier and the second creates some variety instead of just a drawn out combat encounter. To add onto these ideas though, I recently had a siege storyline at the Martikov Winery and something my players enjoyed was that I gave them the opportunity to gather intel on the attackers and to place traps throughout the property. It really adds to the dread of knowing the siege is coming and helps give the players more agency during an event that otherwise going to be pretty linear..
I realised how easy development work is and how amiss I’ve been all these years. Now I hop from Indira Nagar to Valmiki Nagar to Gandhi Nagar on Sundays looking for people whose feet I can wash. There are beggars and hawkers, pickpockets and college youths, auto drivers and stray cows.
A screening cascade comprised of an MTT assay, a caspase 3 activation assay, a p53 stabilization assay and a mitotic index assay was developed to classify compounds and identify lead transcriptional CDK inhibitors from a novel class of 2,4,5 trisubstituted pyrimidines. Compounds S3 41 and CDKI 71 are the most potent CDK9 inhibitors identified by the screening cascade. They showed potent anti proliferative activity in the MTT assay and induce both caspase 3 activity and p53 protein level at the GI50 concentration.
When calling, be sure to include the name and address of the merchant as well as the price and receipt of the item or service.UHAUL is providing 30 days of free storage in several outlying cities for those displaced by the storm. Check the list here.Calcasieu Parish Police Jury offices and facilities will reopen to the public Monday, October 5th for the first time since Hurricane Laura made landfall August 27th. Parish residents are asked to be aware that due to storm damage and the ongoing COVID 19 pandemic that some services may be limited or relocated.Calcasieu Parish Libraries most of the 13 library branches will open Wednesday, Oct.
Former President Donald Trump impeachment defense has already wrapped up. Trump lawyers on Friday afternoon concluded their arguments in the former president impeachment trial about three hours after they began, ultimately only using two and a half hours to make their case when discounting a break. Both sides in the impeachment trial were allotted 16 hours over two days for their arguments.
The Afghanistan war veteran burst onto the national scene in 2019 after launching a longshot presidential bid, introducing himself to voters as Pete and drawing initial skepticism due to his youth and limited government experience. He outperformed expectations after zeroing in on a message of generational change, finishing the first in the nation Iowa caucuses in a virtual tie with Vermont Sen. Bernie Sanders..